Exploring Cellular Pathways of Saturated Fatty Acid Toxicity
نویسندگان
چکیده
منابع مشابه
Saturated fatty acid intake and cardiovascular risk.
Since the 1960s, clinical and animal studies have shown that reduction of dietary saturated fatty acid (SFA) consumption is associated with reduced risk of cardiovascular disease (CVD). Thus, reduction of SFA intake is now one of the central strategies of dietary recommendations to reduce CVD worldwide. For example, the World Health Organization and the US Dietary Guidelines recommend dietary c...
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Therapies that target tumor metabolism represent a new horizon in anticancer therapies. In particular, cancer cells are dependent on the generation of lipids, which are essential for cell membrane synthesis, modification of proteins, and localization of many oncogenic signal transduction enzymes. Because fatty acids are the building blocks of these important lipids, fatty acid synthase (FASN) e...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.796.12